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Researchers
Gary Naglie
MD, FRCPC, FGSA
Identifying ways to measure quality of life in frail elderly

For Dr. Gary Naglie, it was a distinct honour to look after a 103-year-old patient. "Being able to converse with someone who's experienced that much life is a gift," says Dr. Naglie, clinical researcher at Toronto Rehab. "I appreciate the chance to know someone who's seen society evolve from the horse and buggy era to the modern age."

Dr. Naglie's research looks at outcomes in frail older populations such as elderly people with hip fractures, dementia or on dialysis. His focus has been on evaluating programs and interventions for these people and trying to establish what outcomes to measure in order to assess how effective therapy is.

"I'm particularly interested in quality of life. We're doing a major study on quality of life in Alzheimer's disease, trying to assess a variety of measures. We also want to compare patients' own rating of their quality of life with those of caregivers and to evaluate how quality of life in Alzheimer's patients changes over time."

Measuring quality of life can be controversial. Dr. Naglie's study will use a variety of different measures to try and provide greater insights into quality of life in this patient population.

 "A pilot study we did suggested patients with mild to moderate dementia reliably provide information about their own quality of life," says Dr. Naglie. "And, generally speaking, patients rated their quality of life much higher than their caregivers did. That raises interesting clinical and research issues about how to measure quality of life and how to interpret those measurements."


Dr. Gary Naglie
Quick Biography

Dr. Naglie is a clinical researcher in geriatric medicine at Toronto Rehab. He holds the Mary Trimmer Chair in Geriatric Medicine Research from the University of Toronto. Associate Professor in the Departments of Medicine and Health Policy, Management and Evaluation at the University of Toronto, he is a geriatrician at University Health Network and senior scientist at Toronto General Research Institute. His research centres on outcomes in the frail elderly, including quality of life assessment and cost-effectiveness analysis of interventions for older persons. He has expertise in drug policy and evaluation. Dr. Naglie has published and lectured extensively on geriatric medicine. He has an MD from McGill University and did postgraduate training at the University of Toronto and McMaster University.

Finding ways to measure QOL is important for several reasons. For one thing, many drugs are being developed to treat Alzheimer's disease. To properly evaluate these drugs - or other interventions - scientists must learn more about how to measure quality of life.

Dr. Naglie is also doing an ongoing study of different outcome measures to evaluate the effectiveness of Toronto Rehab's Geriatric Rehabilitation Program. This program focuses on developing initiatives to meet the unmet needs of the frail elderly population. One such need was dialysis for the elderly. In 2002, the hospital added a specialty care program for elderly hemodialysis patients. A dialysis unit now provides on-site dialysis.

Dr. Naglie has always enjoyed the company of elderly people. "I had a very close relationship with my grandparents. Like many colleagues in this field I have had some very positive experience with the elderly. In a society that values physical youthfulness it's easy to overlook the positive aspects of growing older.

"What strikes me the most about older people is their tremendous sense of humour. Either having a sense of humour helps you live longer or, as you become older, it becomes important to view the world in a humorous way."

Dr. Naglie holds Fellowships from the Royal College of Physicians and Surgeons of Canada in geriatric and internal medicine. He is the first holder of the Mary Trimmer Chair in Geriatric Medicine Research from the University of Toronto. He is a consultant geriatrician at the University Health Network and Toronto Rehab and Associate Professor in the Departments of Medicine and Health Policy, Management & Evaluation at the University of Toronto.

Publications 2002 - present

Curriculum Vitae

 

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